Patients who received botulinum toxin injections at various sites for different conditions reported depression significantly less often, compared with patients undergoing different treatments for the same conditions, according to a study published in Scientific Reports.
“For years, clinicians have observed that Botox injected for cosmetic reasons seems to ease depression for their patients,” said researcher Ruben Abagyan, PhD, professor of pharmacy at the University of California San Diego. “It’s been thought that easing severe frown lines in the forehead region disrupts a feedback loop that reinforces negative emotions. But we’ve found here that the mechanism may be more complex, because it doesn’t really matter where the Botox is injected.”
The finding stems from an analysis of 40,000 botulinum toxin treatment reports in the US Food and Drug Administration (FDA) Adverse Event Reporting System.
People who received botulinum toxin injections at 6 different sites for the treatment of conditions such as hyperhidrosis, facial wrinkles, migraine prophylaxis, spasticity, and spasms reported depression 40% to 88% less often than patients who received other treatments for the same conditions, according to the study.
Although the data used in the study was not collected for the purpose of exploring a link between botulinum toxin injections and depression and represents a subset of patients who experienced negative side effects, researchers believe the findings point to a significant antidepressant effect across a broad range of injection sites.
“This finding is exciting because it supports a new treatment to affect mood and fight depression, one of the common and dangerous mental illnesses—and it’s based on a very large body of statistical data, rather than limited-scale observations,” said Tigran Makunts, PharmD, a research fellow at the FDA.
Makunts T, Wollmer MA, Abagyan R. Postmarketing safety surveillance data reveals antidepressant effects of botulinum toxin across various indications and injection sites. Scientific Reports. 2020;10(1):12851. 
- ^ depression (www.psychcongress.com)
- ^ Botox Reduces Treatment-Resistant Symptoms of BPD (www.psychcongress.com)
- ^ Makunts T, Wollmer MA, Abagyan R. Postmarketing safety surveillance data reveals antidepressant effects of botulinum toxin across various indications and injection sites. Scientific Reports. 2020;10(1):12851. (www.nature.com)
- ^ Buschman H. Botox injections may lessen depression [press release]. San Diego, California: UC San Diego Health; July 30, 2020. (health.ucsd.edu)
Source URL: Read More
The public content above was dynamically discovered – by graded relevancy to this site’s keyword domain name. Such discovery was by systematic attempts to filter for “Creative Commons“ re-use licensing and/or by Press Release distributions. “Source URL” states the content’s owner and/or publisher. When possible, this site references the content above to generate its value-add, the dynamic sentimental analysis below, which allows us to research global sentiments across a multitude of topics related to this site’s specific keyword domain name. Additionally, when possible, this site references the content above to provide on-demand (multilingual) translations and/or to power its “Read Article to Me” feature, which reads the content aloud to visitors. Where applicable, this site also auto-generates a “References” section, which appends the content above by listing all mentioned links. Views expressed in the content above are solely those of the author(s). We do not endorse, offer to sell, promote, recommend, or, otherwise, make any statement about the content above. We reference the content above for your “reading” entertainment purposes only. Review “DMCA & Terms”, at the bottom of this site, for terms of your access and use as well as for applicable DMCA take-down request.
Acquire this Domain
You can acquire this site’s domain name! We have nurtured its online marketing value by systematically curating this site by the domain’s relevant keywords. Explore our content network – you can advertise on each or rent vs. buy the domain. Buy@TLDtraders.com | Skype: TLDtraders | +1 (475) BUY-NAME (289 – 6263). Thousands search by this site’s exact keyword domain name! Most are sent here because search engines often love the keyword. This domain can be your 24/7 lead generator! If you own it, you could capture a large amount of online traffic for your niche. Stop wasting money on ads. Instead, buy this domain to gain a long-term marketing asset. If you can’t afford to buy then you can rent the domain.
We are Internet Investors, Developers, and Franchisers – operating a content network of several thousand sites while federating 100+ eCommerce and SaaS startups. With our proprietary “inverted incubation” model, we leverage a portfolio of $100M in valued domains to impact online trends, traffic, and transactions. We use robotic process automation, machine learning, and other proprietary approaches to power our content network. Contact us to learn how we can help you with your online marketing and/or site maintenance.