Int J Gen Med. 2013; 6: 323–328. This article has been cited by[1] other articles in PMC. Abstract Objectives Constipation is a common complaint, frequently treated with cleansing enema. Enemas can be very effective but may cause serious adverse events, such as perforation or metabolic derangement. Our aim was to evaluate the outcome of the use of cleansing enema for...

View and print full Drug Safety Communication (PDF – 218KB)[1] Safety Announcement [1-8-2014] The U.S. Food and Drug Administration (FDA) is warning that using more than one dose in 24 hours of over-the-counter (OTC) sodium phosphate drugs to treat constipation can cause rare but serious harm to the kidneys and heart, and even death. OTC sodium phosphate drug products include...

Introduction Orally ingested alcohol does not cause damage to the upper gastrointestinal tract. However, in an animal experiment, mucosa of the rat colon was damaged with 10% alcohol.1 Here, we report the case of a patient who experienced extensive chemical proctocolitis by transanally administering a large quantity of 35% alcohol, with a review on the clinical course of previous reports....